智財技轉處 Department of Intellectual Property and Technology Transfer 智財技轉處 Department of Intellectual Property and Technology Transfer

本院覽號：28A-970530

創作人：Alice Yu, You-Chin Lin, Ruey-Jen Lin

智財權：US Provisional

摘要：

Neuroblastoma (NB) is a common childhood tumor derived from primitive sympathetic neuroblasts and accounts for 15% of pediatric cancer deaths. Although current risk stratification is useful for selection of appropriate therapeutic regimens, there is still a lack of useful markers for predicting treatment failure in lower risk patients and high risk patients.

The invention relates to progmostic markers specific for neuroblastoma that can predict tumor behavior and refine risk assessment in a patient diagnosed with neuroblastoma, and more particularly to methods for delineating neuroblastoma patients into clinical risk groups by observing MicroRNA signature and expression of Dicer and Drosha.

智財技轉處聯絡人：林哲毅 / 02-2787-2550 / cephaso@gate.sinica.edu.tw