本院覽號:28A-941103
創作人:Chi-Huey Wong, Pi-Hui Liang, Yi-Ling Lin
智財權:US 7919521 B2
摘要:
A novel 5-membered iminocyclitol derivative is found to be a potent and selective inhibitor of the glycoprotein processing α-glucosidase. It has alos been shown as effective further developed into antiviral agent against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus. In addition, it can inhibit human β-hexoaminidase, a new target for development of osteoarthritis therapeutics.
可能的應用範圍:
Antivirals and Osteoarthritis Therapeutics
此項發明的優點:
- Novel compound
- Low IC 50
- New target for development of osteoarthritis therapeutics
智財技轉處聯絡人:張書銘 / 02-2787-2600 / name4517@gate.sinica.edu.tw