智財技轉處 Department of Intellectual Property and Technology Transfer 智財技轉處 Department of Intellectual Property and Technology Transfer

本院覽號：28A-941103

創作人：Chi-Huey Wong, Pi-Hui Liang, Yi-Ling Lin

智財權：US 7919521 B2

摘要：

A novel 5-membered iminocyclitol derivative is found to be a potent and selective inhibitor of the glycoprotein processing α-glucosidase. It has alos been shown as effective further developed into antiviral agent against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus. In addition, it can inhibit human β-hexoaminidase, a new target for development of osteoarthritis therapeutics.

可能的應用範圍：

Antivirals and Osteoarthritis Therapeutics

此項發明的優點：

1. Novel compound
2. Low IC 50
3. New target for development of osteoarthritis therapeutics

智財技轉處聯絡人：張書銘 / 02-2787-2600 / name4517@gate.sinica.edu.tw