創作人：Chi-Huey Wong, Pi-Hui Liang, Yi-Ling Lin
智財權：US 7919521 B2
A novel 5-membered iminocyclitol derivative is found to be a potent and selective inhibitor of the glycoprotein processing α-glucosidase. It has alos been shown as effective further developed into antiviral agent against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus. In addition, it can inhibit human β-hexoaminidase, a new target for development of osteoarthritis therapeutics.
Antivirals and Osteoarthritis Therapeutics
- Novel compound
- Low IC 50
- New target for development of osteoarthritis therapeutics
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