Publish time： 2022-12-06 00:00:00
11A-1100408
TW I837825、PCT pending
BP is a common gut microorganism in Taiwanese population. The abundance of BP was significantly lower our cohort of colon cancer patients compared with general population. Patients with colon surgery indicated that the loss of BP was persistent after 12 month of observation.
Therefore, we apply a diet-mediated BP using SFP mice and BP along oral gavage using a colon cancer model. Our results indicated that colonization of BP can suppress tumor formation in this mouse model. Further investigation suggested that BP can suppress colon inflammation and tumor cell proliferation.
- This case is derived from real-world data
- Ability to regulate strains in specific dietary patterns
- This invention can be applied in multiple uses
- Probiotics, Prebiotics
- Special diets, functional meals
- Fecal Microbiota Transplantation
- Microbiome Array
Tzu-Ching Meng, Fu-Tong Liu, Hung-Lin Chen, Chang Shan Chen
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The potential usage of BP for colon cancer prognosis marker after surgery